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This document has been prepared to help provide you with information about Hyperhidrosis (excessive sweating) treatment using Botox®, its risks, and alternative treatments. It is important that you read this information carefully and completely. Although the majority of patients do not experience these complications, you should discuss each of them with your NoviSkin physician to make sure you understand the risk, potential complications and consequences of laser skin treatment.


Hyperhidrosis means excessive sweating. Sweating is one of the most important ways the body gives off heat, however, people with hyperhidrosis produce sweating amounts far greater than needed to control their temperature. It has been estimated that up to 1% of the population has some form of hyperhidrosis. It usually starts during the teens and twenties.


Focal hyperhidrosis is the more common type involving excessive sweating of the feet, palms and in 30 – 40% of cases, the armpits. The face may also be affected but less than 10%. Even less, is gustatory hyperhidrosis, when spicy or hot food triggers excessive sweating on the face and scalp.

Treatment of choice is Botulinum Toxin filler for focal axillary hyperhidrosis.


  • Genetic predisposition
  • Exercise
  • Heat or cold
  • Alcohol
  • Coffee and tea
  • Smoking
  • Hot and spicy food
  • Stress, anxiety and strong emotions
  • Certain times of the day

Mechanism of action

Botox® is a pure preparation of a protein, Botulinum Toxin Type A, which is obtained from Bacteria Clostridium Botulism grown under modern methods of cultivation. When small amounts of Botox® are injected into the skin, it blocks the actions of the nerves that supply the eccrine glands. This prevents the glands from producing sweat.

New nerve endings grow within 12 weeks, which means that the effects of the treatment will last a few months.


Please find below a basic overview of the treatment protocol for Hyperhidrosis using Botox®.

  • The armpit area is disinfected.
  • Alcohol based iodine is then wiped over the area concerned.
  • Corn starch powder is scattered onto the iodine based area.
  • Purple droplets will appear when the sweat interacts with the corn-starch and iodine.
  • A dotted area is demarcated and will be the area injected with Botox®.
  • Using a very fine needle, a NoviSkin physician will inject a small amount (0.1ml – 0.2 ml) of solution of Botox® into numerous areas in the armpit area, 1cm apart and evenly distributed.

Alternative Treatments

Alternative hyperhidrosis treatment options include:

  • Systemic medications
  • Endoscopic thoracic sympathectomy surgery


It is advised that you do not undergo Hyperhidrosis treatments should you be affected by any of these contra-indications:

  • Hypersensitivity to Botox®
  • Pregnancy or breast feeding
  • Infection at proposed site
  • If you are taking any muscle relaxant
  • If you are on any blood thinners
  • Patients who suffer with muscle problems
  • Surgery done in the armpit area

Risks / Side Effects

Please find below a list of common side effects and risks, for a more comprehensive list and explanation, please refer to the consent form and discuss this with your NoviSkin doctor.

If you undergo hyperhidrosis treatment with Botox® you can experience:

  • Flu-like symptoms which disappear after a few days
  • Discomfort at the injection site
  • 4% of patients reported increase sweating in other areas
  • 0.7% of patients reported arm weakness, which resolved without any treatment

Contact NoviSkin immediately on 012 460 4646/50 if you experience any of the following:

  • Difficulty breathing, swallowing or speaking
  • Hives
  • Swelling of the face or throat
  • Signs of a severe allergic reaction

If you decide to stop treatment, there will be no long-lasting change and the level of sweat will slowly return to the level it initially was.

Pre and Post Care Instructions

  • Avoid alcohol consumption for 12 hours
  • Avoid applying antiperspirant for 12 hours
  • Do not rub the area for 24 hours
  • Do not lie down or do strenuous exercise for 4 hours after treatment
  • Avoid sun exposure and extreme temperatures and saunas for 2 weeks after treatment
  • The patient will see results about 14 days after treatment
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