This document has been prepared to help provide you with information about PRP Therapy of the skin, or as it is called at NoviSkin – Vampire Facial – its risks, and alternative treatments. It is important that you read this information carefully and completely.
Platelet rich plasma (PRP) is the cell free plasma containing a higher than normal concentration of human platelets per volume. Treatment with PRP has become an increasing clinical tool used for tissue argumentation and bone regeneration. This includes:
- Facial rejuvenation therapy for wrinkles and solar damage skin
- Surgery-free repair of sports injuries
- Cutaneous wound healing
PRP therapy is a treatment option if you are presenting with any of these indications:
- Reduction of downtime after invasive aesthetic procedures
- Sun damage
- Burn wounds
- Fine lines and wrinkles
- Dehydrated skin
- Radiance optimizing
- Areas treatable: Face, neck décolletage area
Step 1: Blood collection
As your own (autologous) blood is used, it is first collected by venesection, the same procedure used in blood tests or blood donations. The site of the venesection is usually a large vein in your elbow. Up to 20ml of blood may be collected.
Step 2: Centrifuge
The blood will then be spun down in a centrifuge to separate the components. The process takes 15 minutes. The platelet-rich plasma (PRP) is then harvested and there are a variety of different ways this can be done with a CelluVance™ kit. Anti-ageing therapies require between 2-8ml of PRP which will then be extracted from the centrifuged blood.
Step 3: Injection
Involves injecting the prepared solution into the different layers of the skin using different injecting technique namely:
- Superficial nappage – superficial injections to the epidermal layer = 1mm depth.
- Superficial intradermal- Multiple papules 2mm, made to the intrabasal layer.
- Deep intra dermal – Point by point injections = 4 – 10 mm depth
Mechanism of action
When the concentrated platelets in the PRP are activated, it mimics the wound-healing cascade and accelerates recovery by releasing a variety of cytokines and growth factors. This results in a new formation of extracellular proteins such as collagen. In practice treatment with PRP is made possible by easily obtaining autologous PRP with the aid of commercial kits.
The CelluVance™ kits use the patient’s own blood to stimulate the collagen production ensuring that is no risk of contamination with any transmissible diseases. The kit concentrates platelets via a centrifugal step in special CE tubes followed by a safe and effective thrombin free activation method.
Given that PRP Therapy can treat many indications, please discuss alternative options specific to your aesthetic needs. Some alternative treatments can include:
- Botulinum toxin
- Dermal fillers
- Chemical Peels
It is advised that you do not undergo PRP therapy should you be affected by any of these contra-indications:
- Cancer or metastatic disease
- An open wound on the or an active infection
- A low platelet count
- Auto-immune diseases
- Poor wound healing or Keloidosis
- Patients on anticoagulants
- Skin cancers
Risks / Side Effects
Please find below a list of common side effects and risks, for a more comprehensive list and explanation, please refer to the consent form and discuss this with your NoviSkin physician. Pain and burning: mild irritation may occur during the injection process but local anaesthetic is applied to skin to ensure the treatment is comfortable. Redness and swelling may occur but that will resolve in 2 days Bruising around the delicate areas (i.e. eye area) may occur but will resolve in 7 – 10 days Skin discolouration and temporal numbness may occur which is rare but will resolve after 3 months. Scarring may occur at the injection site if post-treatment protocol was not performed correctly.
Pre and Post Care Instructions
Patient can experience some redness, which should resolve within 24 hours. There is no downtime and patients can continue with normal skin care regime after 48 hours. The remaining clear blood extract is used to sterilize the treated area and no post care cream is needed. This will immediately reduce swelling and redness. Bruising is common if delicate or sensitive areas are to be treated but this will resolve within 7 – 10 days. Scabs from wound healing should not be picked or removed, as it can result in pigmentation or scarring. If a patient experiences any side effects other than above mentioned, they should contact NoviSkin immediately.